News & Features

The world of MS information changes rapidly. Breakthroughs in understanding the mechanisms of MS, its cause, and its treatment come at a rapid pace. And there's so much to know just about managing the disease in your daily life! 

To keep you informed and up-to-date, MS Focus offers informative periodicals and round-the-clock multimedia broadcasting. Whether print or digital, these materials are designed to be easy to understand for MS patients, their families, and care providers. Subscriptions are free of charge.

BMI, but not age at puberty, tied to MS risk

March 22, 2019

If so, this could be another important reason for public health initiatives to focus on lowering obesity rates.
Learn more

Study: MS may not worsen after pregnancy after all

March 18, 2019

Researchers said this shows that women with MS today can have children, breastfeed and resume their treatment without experiencing an increased risk of relapses during the postpartum period.
Learn more

Noncontrast MRI is effective in monitoring MS patients

March 14, 2019

The findings support the possibility that contrast enhancement can be omitted from routine follow-up scans.
Learn more

Soda, sugar-sweetened drinks linked to more severe MS symptoms

March 12, 2019

The study found that participants who consumed the largest amounts of sugar-sweetened beverages were five times more likely to have severe disability than people who seldom drank sugar-sweetened beverages.
Learn more

Cocoa may help curb fatigue typically associated with MS

March 08, 2019

Researchers suggest cocoa may offer an easy, safe approach to the persistent symptom, if confirmed.
Learn more

Researchers identify how metabolites target T cells to treat MS

March 01, 2019

The discovery could lead to novel, more specific, and more effective MS therapies.
Learn more

MySupportHero honors those who support the MS community

March 01, 2019

We are excited to be working with Biogen and other MS organizations to bring back #MySupportHero — a program designed to celebrate those who provide invaluable support and inspiration for people living with MS.
Learn more

Study links MS disability progression to income, education

February 27, 2019

The findings paint a clearer picture of the way that wealth and education might affect patients with MS.
Learn more

Study: Chloroindazole compounds show promise as treatments 

February 25, 2019

New compounds offer the protective effects of estrogen without the unpleasant side effects
Learn more

BMI, but not age at puberty, tied to MS risk

March 22, 2019

If so, this could be another important reason for public health initiatives to focus on lowering obesity rates.
Learn more

Study: MS may not worsen after pregnancy after all

March 18, 2019

Researchers said this shows that women with MS today can have children, breastfeed and resume their treatment without experiencing an increased risk of relapses during the postpartum period.
Learn more

Noncontrast MRI is effective in monitoring MS patients

March 14, 2019

The findings support the possibility that contrast enhancement can be omitted from routine follow-up scans.
Learn more

Soda, sugar-sweetened drinks linked to more severe MS symptoms

March 12, 2019

The study found that participants who consumed the largest amounts of sugar-sweetened beverages were five times more likely to have severe disability than people who seldom drank sugar-sweetened beverages.
Learn more

Cocoa may help curb fatigue typically associated with MS

March 08, 2019

Researchers suggest cocoa may offer an easy, safe approach to the persistent symptom, if confirmed.
Learn more

Researchers identify how metabolites target T cells to treat MS

March 01, 2019

The discovery could lead to novel, more specific, and more effective MS therapies.
Learn more

MySupportHero honors those who support the MS community

March 01, 2019

We are excited to be working with Biogen and other MS organizations to bring back #MySupportHero — a program designed to celebrate those who provide invaluable support and inspiration for people living with MS.
Learn more

Study links MS disability progression to income, education

February 27, 2019

The findings paint a clearer picture of the way that wealth and education might affect patients with MS.
Learn more

Study: Chloroindazole compounds show promise as treatments 

February 25, 2019

New compounds offer the protective effects of estrogen without the unpleasant side effects
Learn more

Study finds food allergies and MS link

February 22, 2019

This link between food allergies and MS disease activity highlights an important role of the gut.
Learn more

Regulating the MS-causing properties of Th17 cells

February 19, 2019

A new study identifies a protein regulator responsible for inducing the pathogenic properties of Th17 cells, leading to multiple sclerosis. A research team from Osaka University found that the protein Satb1 triggers a shift in immune cells, causing tissue inflammation and autoimmunity. This breakthrough could lead to new treatments targeting the source of inflammation.

Interleukin 17-producing T-helper cells are a recently-identified class of immune cells that play a major role in protection against invading pathogens. Studies have shown that excessive inflammation induced by Th17 cells is actually one of the underlying causes of many inflammatory and autoimmune disorders. But what causes Th17 cells to cross the line from helpful to harmful? To answer this question, the researchers examined genome organizer protein Satb1.

Using a mouse model of MS, the researchers deleted the Satb1 gene in Th17 cells and found that the disease no longer developed in the mice. Key to this mechanism was the lack of expression of a protein called granulocyte-macrophage colony-stimulating factor by the Satb1-defective Th17 cells. GM-CSF is a pathogenic cytokine that causes localized tissue inflammation in MS. Satb1 was also found to enhance the expression of the GM-CSF gene, confirming its role in promoting inflammation.

Satb1 also blocks the expression of a protein specially designed to suppress T-cell inflammatory activity and prevent autoimmune diseases. This protein, programmed cell death protein 1, was more highly expressed in Satb1-deficient Th17 cells compared with normal Th17 cells, indicating that Satb1 normally inhibits protein expression.

Results of mouse model studies sometimes do not translate to humans and may be years away from being a marketable treatment. However, the researchers said the results suggest that manipulating Satb1 gene expression in Th17 cells could form the basis of novel treatments for various autoimmune diseases caused by Th17 cells. If they can prevent the pathogenic processes of Th17 cells, they may be able to alleviate or even eliminate disease symptoms.

The study was published in Nature Communications.
Learn more

Researchers: Immune system master switch key to new treatments

February 14, 2019

According to the study’s authors, the discovery could be translated into a viable drug treatment for MS within a few years.
Learn more

Newly discovered immune cells may play role in MS

February 06, 2019

The single-cell analyses used by the researchers are new and can be used for studying individual cells from tissues.
Learn more

Brain cell changes in people with MS revealed

January 30, 2019

The findings could shed new light on how the disease progresses and help scientists develop treatments.
Learn more

Nerve degeneration by calcium ions may contribute to MS

January 29, 2019

A new study suggests that ruptures in the cell membrane initiate degeneration of long nerve fibers, resulting influx of calcium ions.
Learn more

Researchers conducting online survey on heat, cold, and MS

January 28, 2019

The survey specifically focuses on what methods patients use to cope with the symptom worsening induced by exposure to heat and cold.
Learn more

Brain regeneration mechanism may help trigger remyelination

January 25, 2019

The findings may provide a basis for the development of new drugs to treat MS.
Learn more

MS Coalition seeks participants for secondary progressive survey

January 24, 2019

A survey has been developed to gain patient input into secondary progressive MS.
Learn more


Show More News