Study: Salt can trigger MS inflammation

October 30, 2018
Yale researchers identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis.

The study’s authors said cells in a high-salt environment show activation of the beta-catenin/Wnt signaling pathway. This pathway disrupts regulatory T cells and triggers inflammation.

The risk of developing MS is thought to increase by interaction between relatively common genetic variants and environmental factors. In addition to salt, vitamin D deficiency, smoking, and obesity have been linked to development of MS.

The study was published in the journal Nature Immunology.

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